Opportunity Information: Apply for 72067423RFA00001

Accelerate TB Elimination and Program Resilience Activity 2 (ACCELERATE 2) is a USAID/South Africa funding opportunity designed to help South Africa move faster toward tuberculosis (TB) elimination by strengthening the full chain of TB services: finding cases earlier, ensuring people receive the right treatment and care (including for more complex forms of TB), and improving prevention among populations at higher risk. The activity is positioned as part of USAID/SA's flagship TB effort, with an emphasis on practical, on-the-ground support that improves how TB services are delivered and sustained. A central theme is resilience, meaning the program is meant to help systems and services keep performing even under strain, such as shifting health demands, resource constraints, or disruptions.

This opportunity is specifically for the second of two related USAID activities under the broader ACCELERATE project. While ACCELERATE 1 focuses on technical support and interventions at the national and provincial levels and in high TB burden districts, ACCELERATE 2 targets the provincial, district, facility, and community levels in lower TB burden districts. The logic is that TB elimination can be advanced by "fast tracking" progress in places where TB burden is lower, using targeted interventions to push these districts closer to elimination sooner while still supporting vulnerable and high-risk groups within those areas. In other words, ACCELERATE 2 is structured to make lower-burden districts demonstrate elimination gains more rapidly, contributing to national momentum and lessons that can be applied elsewhere.

Programmatically, the activity prioritizes early detection and effective treatment, including attention to drug-resistant TB (DR-TB) and TB/HIV co-infection, both of which can complicate diagnosis, clinical management, and retention in care. The description highlights vulnerable populations, signaling that the funded work is expected to concentrate effort where transmission risk, barriers to access, and poor outcomes are more likely. Although the notice does not list individual interventions in the provided text, the framing implies support that strengthens service delivery across the continuum, from identifying people with symptoms and linking them to testing, to ensuring timely initiation of appropriate regimens, to supporting adherence and follow-up, and reinforcing prevention approaches that reduce new infections and recurrence.

From a funding and administrative standpoint, this is a USAID opportunity administered by the Agency for International Development, South Africa (USAID-Pretoria). The funding instrument is a Cooperative Agreement, which typically indicates substantial involvement by the funder during implementation, such as collaboration on technical direction, monitoring, coordination, and learning. The opportunity category is listed as "Other," and the activity category is Health. The CFDA (assistance listing) number provided is 98.001. The funding opportunity number is 72067423RFA00001.

Financially, the opportunity lists an award ceiling of $47,000,000 and anticipates making 1 award, indicating a single prime implementer is expected to lead the activity at scale. The posting was created on November 18, 2022, with an original closing date of January 19, 2023. Eligibility is shown as "Others," with clarification referenced in an additional eligibility information field (not included in the excerpt), meaning applicants would need to consult the full announcement for precise eligibility rules, such as allowable organization types, registration requirements, or local partner expectations.

Overall, ACCELERATE 2 can be understood as a large, single-award USAID cooperative agreement intended to deliver district-to-community level TB technical support and service strengthening in lower-burden South African districts, with the explicit goal of accelerating progress toward TB elimination through earlier case finding, stronger treatment and care (including DR-TB and TB/HIV), and improved prevention among vulnerable populations.

  • The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Accelerate TB Elimination and Program Resilience Activity 2" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on Nov 18, 2022.
  • Applicants must submit their applications by Jan 19, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $47,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for 72067423RFA00001

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