Opportunity Information: Apply for RFA MH 17 255

The BRAIN Initiative: Data Archives for the BRAIN Initiative (R24) funding opportunity (RFA-MH-17-255) is a National Institutes of Health (NIH) discretionary grant program focused on building and operating web-accessible data archives that support the broader BRAIN Initiative research ecosystem. The central purpose is to create robust, community-facing repositories that can capture, store, and curate datasets generated through BRAIN Initiative activities, and then make those data broadly available so other researchers can find, understand, and reuse them. In practical terms, NIH is looking for applicants who can stand up an archive that functions as a long-term community resource, not just a project-specific database, with strong attention to data stewardship, discoverability, and usability for downstream science.

A key emphasis of the announcement is that the archive should be designed in collaboration with the research community, especially around features that help users work with the data. The archive is expected to incorporate (or integrate with) tools that allow users to analyze and visualize datasets, because those capabilities make an archive far more useful than a simple storage site. At the same time, the FOA draws a clear boundary: building new analysis/visualization tools is not the main deliverable being funded here. Similarly, the archive should apply appropriate data standards and structured descriptions (metadata) so that users can interpret what the data mean and how they were produced, but the development of brand-new standards is also outside the scope of this FOA. The intent is to leverage and implement existing standards and best practices wherever possible, then organize the archive so that data and accompanying summary information are consistently described and easy to navigate.

The overall program goal is to accelerate neuroscience discovery by reducing friction in data sharing and reuse. NIH is prioritizing an archive model that supports curation (quality control, documentation, and organization), accessibility (web-based access for the research community), and broad availability (positioning the archive as a shared infrastructure that enables secondary analyses, comparisons across studies, method development, and replication). While the announcement is framed around BRAIN Initiative data, the expected impact is larger: a well-run archive can become a foundational piece of infrastructure that helps standardize how datasets are packaged, improves transparency, and makes it easier for researchers to build on one another's work.

Eligibility is intentionally broad and includes many types of organizations that can credibly build and manage a national-scale data resource. Eligible applicants listed include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other entities. The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This wide eligibility reflects that data-archive capacity can exist in many settings, including universities, dedicated research institutes, specialized nonprofits, and private-sector organizations with strong informatics infrastructure.

From the source details provided, the opportunity is an NIH grant using the R24 activity code (commonly used for resource-related projects), with a creation date of September 21, 2016, and an original closing date of October 19, 2017. The announcement is associated with multiple CFDA numbers (93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867), reflecting NIH programmatic and institute participation across several funding lines relevant to neuroscience and biomedical data resources. Award ceiling and expected award counts are not specified in the provided excerpt, so the main takeaways for an applicant are the scope and boundaries of work: propose a sustainable, standards-aware, web-accessible archive that curates BRAIN-related data and serves as a widely used community resource, while relying on existing tools and standards rather than treating tool-building or standards-development as the funded centerpiece.

  • The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "BRAIN Initiative: Data Archives for the BRAIN Initiative (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867.
  • This funding opportunity was created on 2016-09-21.
  • Applicants must submit their applications by 2017-10-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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BRAIN Initiative: Standards to Define Experiments Related to the BRAIN Initiative (R24) Apply for RFA MH 17 256

Funding Number: RFA MH 17 256
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BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R24) Apply for RFA MH 17 257

Funding Number: RFA MH 17 257
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BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (U01) Apply for RFA NS 17 003

Funding Number: RFA NS 17 003
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01) Apply for RFA NS 17 004

Funding Number: RFA NS 17 004
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44) Apply for RFA NS 17 007

Funding Number: RFA NS 17 007
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
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BRAIN Initiative: Clinical Studies to Advance Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (UH3) Apply for RFA NS 17 006

Funding Number: RFA NS 17 006
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3) Apply for RFA NS 17 005

Funding Number: RFA NS 17 005
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: SBIR Direct to Phase II Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44) Apply for RFA NS 17 008

Funding Number: RFA NS 17 008
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: Research Career Enhancement Award for Investigators to Build Skills in a Cross-Disciplinary Area (K18) Apply for RFA DA 17 022

Funding Number: RFA DA 17 022
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative Cell Census Network (BICCN) - Specialized Center on Human and Non-Human Primate Brain Cell Atlases (U01) Apply for RFA MH 17 210

Funding Number: RFA MH 17 210
Agency: National Institutes of Health
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BRAIN Initiative Cell Census Network (BICCN) - Specialized Center on Mouse Brain Cell Atlas (U01) Apply for RFA MH 17 230

Funding Number: RFA MH 17 230
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
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BRAIN Initiative Cell Census Network (BICCN) Brain Cell Data Center (U24) Apply for RFA MH 17 215

Funding Number: RFA MH 17 215
Agency: National Institutes of Health
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BRAIN Initiative Cell Census Network (BICCN) Comprehensive Center on Mouse Brain Cell Atlas (U19) Apply for RFA MH 17 225

Funding Number: RFA MH 17 225
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
Funding Amount: Case Dependent
BRAIN Initiative: Proof of Concept Development of Early Stage Next Generation Human Brain Imaging (R01) Apply for RFA EB 17 001

Funding Number: RFA EB 17 001
Agency: National Institutes of Health
Category: Education, Health, Income Security and Social Services
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BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01) Apply for RFA MH 17 260

Funding Number: RFA MH 17 260
Agency: National Institutes of Health
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BRAIN Initiative: Development of Next Generation Human Brain Imaging Tools and Technologies (U01) Apply for RFA EB 17 002

Funding Number: RFA EB 17 002
Agency: National Institutes of Health
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BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01) Apply for RFA NS 17 019

Funding Number: RFA NS 17 019
Agency: National Institutes of Health
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Funding Amount: Case Dependent
BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19) Apply for RFA NS 17 018

Funding Number: RFA NS 17 018
Agency: National Institutes of Health
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Funding Amount: Case Dependent
BRAIN Initiative: Targeted BRAIN Circuits Projects - TargetedBCP (R01) Apply for RFA NS 17 014

Funding Number: RFA NS 17 014
Agency: National Institutes of Health
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Funding Number: RFA AI 16 082
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