Opportunity Information: Apply for RFA AI 19 029

The grant opportunity titled "Emerging Infectious Diseases Research Centers - Coordination Center (U01 Clinical Trial Not Allowed)" (Funding Opportunity Number RFA AI 19 029) is a National Institutes of Health (NIH) cooperative agreement designed to fund a single Coordination Center that supports a broader network of Emerging Infectious Diseases Research Centers (EIDRC). Rather than funding a stand-alone research lab or a set of independent scientific aims, this announcement focuses on building the centralized backbone that helps multiple EIDRC sites work together efficiently, consistently, and securely. The intent is to strengthen preparedness and response-oriented research for emerging infectious disease threats by creating shared systems and shared practices across the centers.

At the core of the program is the expectation that the EIDRC Coordination Center will oversee and coordinate key cross-cutting operational elements of the EIDRCs research projects. This includes data management functions such as establishing common data standards, supporting data capture and quality control, enabling secure storage, and facilitating appropriate data sharing across participating centers. In addition, the Coordination Center is expected to coordinate sample-related infrastructure, including guidance and harmonization for specimen collection, processing, tracking, storage, and potentially distribution. The goal is to ensure that samples and data generated at different sites can be compared, combined, and used collaboratively without the typical friction caused by incompatible formats, inconsistent procedures, or unclear governance.

Another major responsibility highlighted in the announcement is facilitating the sharing of reagents, diagnostics, and other resources across the EIDRC network. In practical terms, this means the Coordination Center would help reduce duplication of effort by organizing how participating centers access and distribute specialized materials, assays, protocols, and tools. The Coordination Center is also expected to actively facilitate collaboration not only among the newly awarded EIDRCs, but also, where appropriate, with other U.S. Government entities and with international agencies. This indicates the program values connectivity and coordination beyond a single funding cohort, with an emphasis on building relationships and mechanisms that enable rapid and organized scientific cooperation in the face of emerging threats.

The award mechanism is a U01 cooperative agreement, which generally indicates substantial NIH programmatic involvement compared to a traditional research project grant. In a cooperative agreement structure, the federal sponsor typically plays an active role in oversight, coordination expectations, and milestone-driven progress, which fits the nature of a Coordination Center that must align multiple sites and stakeholders. The opportunity is explicitly labeled "Clinical Trial Not Allowed," signaling that the proposed work for this award should not include clinical trials as defined by NIH policy; the emphasis is on coordination, infrastructure, and enabling functions that support research centers rather than running interventional clinical studies.

From an administrative standpoint, the opportunity falls under the Department of Health and Human Services, National Institutes of Health, within the Health funding activity category (CFDA 93.855). The posting indicates an award ceiling of $500,000 and anticipates one award, reinforcing that this is intended to support a single centralized Coordination Center rather than multiple parallel coordinating hubs. The opportunity was created on March 4, 2019, with an original closing date of June 28, 2019, meaning it was a time-bound solicitation with a specific application window.

Eligibility is broad and includes a wide range of public and private entities capable of managing multi-site scientific coordination. Eligible applicants include state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other entities as described in the NIH eligibility clarification text. This broad eligibility aligns with the operational nature of the award, where strong coordination, informatics, biorepository logistics, and partnership management capabilities can exist in many types of organizations, not only universities.

In summary, this FOA is about building and running the central coordinating infrastructure for the Emerging Infectious Diseases Research Centers program. The Coordination Center is expected to make the network function as a unified enterprise by standardizing and managing data practices, organizing specimen collection and storage approaches, enabling resource sharing (reagents and diagnostics), and actively promoting collaboration across centers and with relevant government and international partners. The funding structure and single-award design underscore that the funded entity would serve as the primary hub responsible for ensuring the EIDRC network operates in a coordinated, interoperable, and collaboration-ready way.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Emerging Infectious Diseases Research Centers - Coordination Center (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
  • This funding opportunity was created on Mar 04, 2019.
  • Applicants must submit their applications by Jun 28, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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