Opportunity Information: Apply for PAR 20 114

The High-End Instrumentation (HEI) Grant Program (PAR-20-114) is a National Institutes of Health (NIH) discretionary grant opportunity designed to help NIH-supported research teams acquire or upgrade one major piece of cutting-edge, commercially available scientific equipment. The core purpose of the program is to strengthen shared research capability by funding a single high-end instrument or an integrated instrumentation system that will be used by a group of investigators whose work aligns with NIH missions in health and biomedical research. As indicated by the notice (S10 Clinical Trial Not Allowed), the funding is intended for research infrastructure and instrumentation support rather than for proposing or running clinical trials under this award mechanism.

Funding under this program is geared toward expensive, specialized instrumentation that would typically be difficult for individual labs to purchase on their own. The minimum award amount is $600,001, and the maximum award that NIH will provide is $2,000,000. While there is no stated maximum purchase price for the instrument itself, the federal award cap means applicants need to plan for any costs above $2,000,000 through other non-federal or institutional sources if the selected system exceeds the award limit. The opportunity supports purchase or upgrade, which means applicants may propose acquiring a new instrument or improving an existing one, so long as it fits the program intent and is justified by the shared needs of NIH-funded users.

The solicitation specifically mentions a wide range of eligible instrument types to illustrate the intended scale and sophistication. Examples include X-ray diffractometers, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, cell sorters, high-throughput robotic screening platforms, and biomedical imaging systems. The emphasis is on high-end, specialized, commercially available systems, suggesting that the program prioritizes equipment that is broadly enabling for biomedical research, can serve multiple NIH-supported projects, and can be feasibly maintained and operated within an institution as a shared resource.

Eligible applicants include U.S.-based public and state-controlled institutions of higher education, private institutions of higher education, and other eligible organization types permitted by NIH under this opportunity. The announcement explicitly includes several categories of institutions as eligible applicants, such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). These listings reinforce that a broad range of U.S. academic and research institutions, including federally recognized minority-serving and tribal-serving institutions, may apply if they meet NIH requirements and can demonstrate a strong base of NIH-supported investigators who will use the instrument.

At the same time, the opportunity places clear restrictions on foreign involvement. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible to apply, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In practical terms, this means the applicant organization and the supported instrumentation resource must be U.S.-based, and the award cannot be structured to support an overseas component or foreign site as part of the project.

From an administrative standpoint, the funding opportunity is issued by the NIH under CFDA numbers 93.351 and 93.859, and it falls under the Health funding activity category. The opportunity was created on February 18, 2020, with an original closing date listed as June 1, 2020. The award instrument type is a grant, and the program is oriented toward building or enhancing institutional research capacity through shared, high-end equipment that benefits multiple NIH-funded researchers rather than a single investigator or a single narrowly defined project.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351, 93.859.
  • This funding opportunity was created on 2020-02-18.
  • Applicants must submit their applications by 2020-06-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
Apply for PAR 20 114

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