Opportunity Information: Apply for PAR 24 259
The National Institutes of Health (NIH) is offering the Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15 Clinical Trial Not Allowed) funding opportunity (PAR-24-259). This program is designed to help eligible institutions buy modern equipment that improves and updates the day-to-day, research-supporting operations of existing shared-use biomedical research facilities. The focus is on spaces and operations that serve multiple research groups, such as laboratory core facilities, animal research facilities, and other comparable shared research environments. The intent is practical: strengthen the supporting functions that keep biomedical research moving and make facility operations more efficient, reliable, and up to date.
A key point is what this grant will and will not pay for. The NOFO supports equipment that enhances research-related operations in shared facilities, meaning items that improve how the facility functions, supports users, maintains quality, and delivers services. However, it explicitly does not support the purchase of scientific research instruments or their components. In other words, it is not intended to fund the kinds of instruments used directly to perform experiments or generate primary research data (or parts used to build or upgrade those instruments). It also does not support components of building-level infrastructure that only indirectly support research activities. That exclusion is meant to keep the program targeted on facility-level operational modernization rather than general construction, utilities, or large infrastructure systems that are part of the building itself.
The award is offered as a discretionary grant within NIH's health-related funding portfolio (CFDA numbers 93.351 and 93.859). The listed award ceiling is $350,000. The opportunity’s original closing date is September 25, 2026, indicating a multi-year window for submissions within the posted cycle.
Eligibility is broad across U.S.-based organizations that operate or support shared biomedical research facilities. Eligible applicants include public and private institutions of higher education, state and local governments (including county and city/township governments), special district governments, independent school districts, and federally recognized Native American tribal governments. It also includes public housing authorities/Indian housing authorities, tribal organizations that are not federally recognized tribal governments, and a wide range of nonprofit organizations (both 501(c)(3) and non-501(c)(3), as long as they are not institutions of higher education). For-profit organizations (other than small businesses) and small businesses are also listed as eligible, along with other applicant types as allowed under NIH rules. The NOFO also highlights additional eligible categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
At the same time, the program places strict limits on foreign involvement. Non-domestic (non-U.S.) entities are not eligible to apply. Non-domestic components of U.S. organizations are also not eligible to apply, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed. This makes the program effectively domestic-only in both the applicant organization and where the supported activities and resources are situated.
Finally, the activity code indicates that clinical trials are not allowed under this opportunity. The purpose is facility and operational modernization rather than conducting human-subjects clinical research, and applications are expected to stay within that scope.Apply for PAR 24 259
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351, 93.859.
- This funding opportunity was created on 2024-08-02.
- Applicants must submit their applications by 2026-09-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the Modern Equipment for Shared-use Biomedical Research Facilities program (PAR-24-259)?
It is a National Institutes of Health (NIH) funding opportunity titled Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15, Clinical Trial Not Allowed). The program is intended to help eligible institutions purchase modern equipment that improves and updates the day-to-day, research-supporting operations of existing shared-use biomedical research facilities.
What is the main goal of this funding opportunity?
The goal is practical operational modernization: strengthening the supporting functions that keep biomedical research moving by making shared facility operations more efficient, reliable, and up to date.
What kinds of facilities does this program focus on?
The focus is on shared-use biomedical research environments that serve multiple research groups. Examples mentioned include laboratory core facilities, animal research facilities, and other comparable shared research environments.
Does this program support creating a brand-new shared facility?
The description emphasizes improving the operations of existing shared-use biomedical research facilities. Based on the information provided, the intent is to modernize and update operational capabilities in facilities that are already in place.
What types of equipment are supported under this program?
Supported equipment is equipment that enhances research-related operations in shared facilities. In practical terms, this means equipment that improves how a facility functions, supports users, maintains quality, and delivers services as part of day-to-day research support operations.
What types of equipment are explicitly not supported?
The opportunity explicitly does not support the purchase of scientific research instruments or their components. That means it is not meant to fund instruments used directly to perform experiments or generate primary research data, nor parts used to build, upgrade, or enhance those instruments.
Can the grant be used to purchase components or upgrades for scientific instruments?
No. The information provided states the NOFO does not support scientific research instruments or their components, including parts used to build or upgrade those instruments.
Does the program fund building construction or building-wide infrastructure?
No. The program does not support components of building-level infrastructure that only indirectly support research activities. The intent is to keep funding targeted on facility-level operational modernization rather than general construction, utilities, or large infrastructure systems that are part of the building itself.
Is this funding intended to support the conduct of biomedical research experiments?
No. The intent described is to modernize operational capabilities in shared facilities that support research. It is not intended to fund the instruments used to directly conduct experiments or generate primary research data.
Are clinical trials allowed under this opportunity?
No. The activity code is S15 and it is labeled Clinical Trial Not Allowed. Applications are expected to stay within the scope of facility and operational modernization rather than conducting human-subjects clinical research.
What is the maximum award amount?
The listed award ceiling is $350,000.
Is this an NIH discretionary grant program?
Yes. The award is offered as a discretionary grant within NIH's health-related funding portfolio.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with CFDA numbers 93.351 and 93.859.
When is the closing date for this funding opportunity?
The original closing date listed is September 25, 2026, indicating a multi-year window for submissions within the posted cycle.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations that operate or support shared biomedical research facilities. Eligible applicants include public and private institutions of higher education; state and local governments (including county and city/township governments); special district governments; independent school districts; and federally recognized Native American tribal governments.
Are nonprofit organizations eligible?
Yes. A wide range of nonprofit organizations are listed as eligible, including both 501(c)(3) and non-501(c)(3) nonprofits, as long as they are not institutions of higher education.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
Are U.S. territories and possessions eligible to apply?
Yes. U.S. territories or possessions are included among the eligible categories highlighted in the opportunity summary.
Are certain institution types specifically highlighted as eligible?
Yes. The NOFO highlights additional eligible categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also notes faith-based or community-based organizations, eligible federal agencies, regional organizations, and other applicant types as allowed under NIH rules.
Can a non-U.S. (foreign) organization apply?
No. Non-domestic (non-U.S.) entities are not eligible to apply.
Can a U.S. organization apply if the project involves a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible to apply.
Are foreign components allowed in the project?
No. Foreign components (as defined in the NIH Grants Policy Statement) are not allowed under this opportunity. The program is effectively domestic-only for both the applicant and where supported activities and resources are situated.
What is the practical distinction between operational equipment and scientific research instruments in this program?
Operational equipment (supported) is described as equipment that improves how a shared facility functions day to day and delivers research-supporting services. Scientific research instruments (not supported) are instruments used directly to perform experiments or produce primary research data, as well as components used to build or upgrade those instruments.
Is the program focused on shared resources that serve multiple research groups?
Yes. The program is explicitly focused on shared-use facilities and operations that serve multiple research groups, such as cores and animal research facilities.
Is the purpose of the program to modernize general building systems?
No. The information provided indicates the program excludes building-level infrastructure that only indirectly supports research, to keep the focus on facility-level operational modernization rather than general building systems.
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